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Its not a one-size-fits-all answer

All cell lines were cultured in RPMI 1640 media (Gibco) supplemented with 10% Fetal Bovine Serum (FBS) (Gibco), 1% L-Glutamine (Gibco) and 1% Penicillin/Streptomycin (Gibco)

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Studies treating mild to moderate B12 deficiency in older people have failed to provide cognitive benefits: A clinical trial from the Netherlands measured the cognitive response to B12 supplements in people 70 years old with mild B12 deficiency and MMA levels 320 nmol/l (average: ~450 nmol/l)

While some patients report less nausea or improved energy, these findings are largely anecdotal and based on small-scale observational data